LONDON -- Newcastle and Aston Villa, the two remaining English representatives in the UEFA Cup, fell victim to the away goals rule and were eliminated from the draw.


Jose Angel Ciganda scored the lone goal Tuesday night as Athletic Bilbao toppled Premier League leader Newcastle in the second-round, second-leg match in Spain.


At Birmingham, Kaynak Orhan scored the key goal in second-half injury time as Turkish club Trabzonspor, playing with 10 men over the final 13 minutes, lost the game 2-1 yet knocked Villa out of the competition.


While it was a bad night for England it was a perfect night for Spain. All three Spanish clubs in the competition won at home to earn places in the final 16. Two German clubs advanced after rolling to 5-0 victories at home, but French teams lost three of four games, winning only in Moscow.


In Bilbao, Ciganda's 18-meter blast off the right hand of Czech goalkeeper Pavel Srnicek in the 67th minute gave Bilbao, currently in fifth place in the Spanish first division, a 1-0 victory over Newcastle and tied the aggregate score at 3-3.


Bilbao advanced to the third round because it had rallied to turn a 3-0 deficit into a 3-2 loss in the second half of the first leg in England.


"With the benefit of hindsight that was the key time," Newcastle manager Kevin Keegan said. "We were three up and if we could have stayed there we'd have been able to come here, have some fish and paella and enjoy ourselves."


The Magpies were without leading scorer Andy Cole, out for a month with shin splints, and never looked like much of a threat to the Bilbao defense.


Newcastle, suffering its second consecutive defeat, had not lost a game this season before falling 2-0 at Manchester United on Saturday.


Aston Villa 2, Trabzonspor 1. Orhan's close-range volley, following several deflections from a corner kick, was the crucial away goal that effectively sealed Villa's fate. The English club won the game to tie the aggregate at 2-2, but Orhan had also scored the only goal in the Trabzonspor's 1-0 victory in Turkey two weeks ago.


Villa had overturned a similar first-leg deficit to defeat defending champion Inter Milan on penalties in the first round, and appeared on track to do the same thing again when Dalian Atkinson scored in the 77th minute.


The goal came after a penalty was awarded to Villa for a handled ball on the goal line, which produced a red card. Steve Staunton's penalty attempt and Ugo Ehiogu's follow-up were blocked, but Atkinson nailed home the second rebound for the score.


After Orhan's goal, Ehiogu put Villa back ahead with a consolation goal late in injury time.


Real Madrid 4, Dinamo Moscow 0. Real Madrid scored four second-half goals and thoroughly dominated Dinamo Moscow to win 4-0 and advance on a 6-2 aggregate.


Chilean Ivan "the Terrible" Zamorano put Real ahead in the 47th minute, and Argentine Fernando Redondo followed up the 76th with a blistering 15-meter (yard) drive. Daniel Garcia scored two insurance goals in the final two minutes.


Deportivo 4, Tirol Innsbruck 0. At La Coruna, Deportivo the home side erupted with three goals in five minutes -- two by Claudio Barragan -- en route to a 4-0 win over Tirol Innsbruck over Austria. The victory overturned a Tirol's 2-0 victory in the first leg.


Lazio 1, Trelleborgs 0. The Trelleborgs, the Swedish team of part-time players that upset English club Blackburn in the first round, nearly repeated the trick against Lazio in Rome. After a scoreless first leg, Croat striker Alen Boksic scored the winning goal for Lazio five minutes into second-half injury time.


Napoli 2, Boavista 1. Napoli, won 2-1 at home over Boavista of Portugal to advance on a 3-2 aggregate. Massimo Agostini scored a pair of first-half goals.


Bayer Leverkusen 5, Kispest Honved 0. Ulf Kirsten, who was suspended for the first leg, scored a hat trick to lead Bayer Leverkusen past Kispest Honved Budapest of Hungary. The German club advanced on a 7-0 aggregate.


Eintracht 5, Rapid Bucharest 0. Two goals apiece from Anthony Yeboah and Jan Furtok paced Eintracht Frankfurt to victory, overturning a 2-1 first-leg deficit to advance 6-2 on aggregate.


Nantes 2, Textilshchik Kamyshin 1. In steady rain in Moscow, Nicolas Ouedec scored two second-half goals to give Nantes of France a 2-1 victory and a 4-1 aggregate triumph.


Olympique Marseille 3, Sion 1. Marseille, which qualified for the tournament before its relegation to the French second division after a match-rigging scandal, lost on the away goals rule. It defeated Sion of Switzerland 3-1 to tie the aggregate at 3-3, but it wasn't enough to overcome a 2-0 first-leg defeat.


Bordeaux 1, GKS Katowice 1. At Bordeaux, Marek Swierczewski's penalty in the 70th minute tied the score in a 1-1 draw to put GKS Katowice of Poland into the third round. Katowice advanced on a 2-1 aggregate.


Admira Wacker 4, Cannes 2. At Cannes, Admira Wacker raced to a 3-0 lead in the opening 25 minutes and coasted to a 4-2 victory. Laszlo Klausz scored twice for the Austrian team, which advanced on a 5-3 aggregate.