Lomonosov Moscow State University has placed 114th in the latest World University Rankings compiled by British-based education specialists QS Quacquarelli Symonds.
The rankings, published Tuesday, are widely considered to be one of the definitive indicators of global educational performance.
Moscow's State University, or MGU, was the highest-ranked Russian university on this year's 11th edition of the QS list, climbing six places from last year.
The university is the most widely acclaimed educational institution in Russia and was ranked the country's best by Interfax news agency and radio station Ekho Moskvy earlier this summer.
MGU was also cited among the developing world's top 10 universities last December by the Times Higher Education BRICS & Emerging Economies ranking.
In all, 21 Russian universities featured on the list, which ranked 863 universities worldwide.
Joining MGU in the top 400 were St. Petersburg's State University (233rd), Bauman Moscow State Technical University (322nd) Novosibirsk State University (328th), and the Moscow State Institute of International Relations (399th).
Topping the rankings for the third year running is the U.S. Massachusetts Institute of Technology, or MIT, which scored top marks across the board.
Britain's University of Cambridge and Imperial College London came in second and third place, respectively, with the U.S.' Harvard University and Britain's Oxford University coming in fourth and fifth place.
The universities were ranked in accordance with eight different criteria: research, employability, teaching, facilities, internationalization, innovation, specialism and access.