Four people have been detained for throwing rolls of toilet paper over the gate at the U.S. Embassy in Moscow late Saturday night.
Police detained four young people over the incident early Sunday morning, after which they were taken to a nearby police station for questioning, news agency ITAR-Tass reported, citing an unidentified police officer.
There have been a spate of similar protests at embassies recently linked to the ongoing crisis in Ukraine.
On Saturday, Ukrainian activists in Kiev wreaked havoc in front of the Russian Embassy and in retribution Russian lawmaker Vitaly Milonov on Sunday staged a protest at the Ukrainian Consulate in St. Petersburg.
It was unclear whether the "toilet paper protest" was also connected to the ongoing conflict in Ukraine.
A Levada Center poll conducted in late May showed 71 percent of Russians have a negative view of the U.S., compared to 44 percent in January.